When a friend tried to upload some files via Skype to my PC it kept failing, Skype 2.1.0.47 for Ubuntu complained “can’t write to file” as soon as I accepted the upload.
Here’s the solution:
First, I created a world-writable directory
mkdir /home/nick/skype-uploads chmod 777 /home/nick/skype-uploads
I opened the File Transfer dialog, clicked the sprocked icon and selected Change Default Download Directory.... After setting that directory to my fresh skype-uploads dir uploads worked!
Nick Sutterer 
thNx Nick for your solution. this one really baffled me for a long time
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Thank you!
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Thanks, it works for me. 🙂
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